Organization · Venture Capital
Wireframe Ventures
Wireframe Ventures is a venture capital firm based in San Francisco, California, focusing on seed and pre-seed stage investments in technology companies that promote health and sustainability.
Overview
What Wireframe Ventures does
What Wireframe Ventures is
Wireframe Ventures is a venture capital firm based in San Francisco, California, focusing on seed and pre-seed stage investments in technology companies that promote health and sustainability.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2016
- Approximate age
- About 10 years
- Structured capabilities
- Funder
- Last reviewed
- March 31, 2026
Official channels
Find Wireframe Ventures elsewhere
Open the official website or a supported primary organization account.
Capability profile
Wireframe Ventures as a funder
Investment thesis
Wireframe Ventures invests in early-stage technology companies focused on creating scalable solutions for climate change and advancements in healthcare, emphasizing AI and automation.
Focus narrative
Wireframe Ventures primarily invests in seed and pre-seed stage startups within the climate technology, biotechnology, and health sectors. The firm typically invests between $500,000 and $2 million, seeking scalable solutions to climate change and advancements in healthcare through innovative technologies.
Value beyond capital
Wireframe Ventures adds value to its portfolio companies by providing strategic guidance, access to a network of industry experts, and support in securing follow-on funding. The firm emphasizes a strong commitment to diversity and inclusion, with a focus on backing first-time founders and underrepresented minority entrepreneurs.
Terms and economics
- Typical check
- $500,000–$2,000,000
- Sweet spot
- $500,000
Focus and fit
- Stages
- Pre-seed · Seed
- Regions
- North America
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 33
- Recorded notable exits
- Electriphi and Enveda Biosciences
Portfolio context
Notable portfolio companies include: Enveda Biosciences: Focuses on discovering new medicines through the study of life’s chemistry and achieved unicorn status. Mammoth Biosciences: Works on commercializing novel CRISPR systems for expanding biological applications. Electriphi: Provides fleet management and energy optimization software for electric vehicle fleets, acquired by Ford. LevelTen Energy: Offers a platform for corporate energy buyers to find renewable energy solutions, with major partners like Microsoft and Google. Xcimer Energy: Aims to make nuclear fusion power a reality by developing high-energy laser systems. Mycoworks: Bioengineers a sustainable alternative to leather using mycelium.
Common questions
What to know about Wireframe Ventures
Upseed classifies Wireframe Ventures under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
March 31, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.