Organization · Venture Capital
Two River
Two River is a New York-based life sciences venture capital firm that partners with scientific founders and experienced management teams to create, finance, and operate companies in the life sciences sector, focusing on innovative therapies.
Overview
What Two River does
What Two River is
Two River is a New York-based life sciences venture capital firm that partners with scientific founders and experienced management teams to create, finance, and operate companies in the life sciences sector, focusing on innovative therapies.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2004
- Approximate age
- About 22 years
- Structured capabilities
- Funder
- Last reviewed
- May 6, 2026
Official channels
Find Two River elsewhere
Open the official website or a supported primary organization account.
Capability profile
Two River as a funder
Investment thesis
Two River focuses on creating life science companies by partnering with scientific founders and experienced management teams. The firm emphasizes strong intellectual property and proven leadership to develop innovative therapies that transform patient outcomes.
Focus narrative
Two River invests in the life sciences sector, specifically targeting groundbreaking science with the potential to transform patient outcomes. The organization supports scientific founders in advancing research from bench to bedside, providing capital, operational capabilities, corporate development, transaction support, and leadership recruitment.
Value beyond capital
Two River adds value to its portfolio companies through hands-on support in product development, regulatory strategy, corporate strategy, transactions, leadership recruitment, and day-to-day operations. The firm’s deep expertise in life sciences enables it to guide companies from inception to successful market entry.
Focus and fit
- Stages
- Pre-seed · Seed · Seed+ · Series A · Series A+ · Series B · Series B+ · Series C · Series C+ · Series D · Series E · Series F · Growth Equity
- Sectors
- Biotech & Life SciencesHealthcareLongevity & Anti-AgingConsumerFintechClimate & SustainabilityArtificial Intelligence
- Regions
- North America · Global
Availability
- Currently deploying
- Not published
Portfolio and track record
- Recorded portfolio count
- 9
- Recorded notable exits
- Neogene Therapeutics and Kite Pharma
Portfolio context
Allogene Therapeutics: Developing allogeneic CAR T therapy for blood cancers and solid tumors. Breakthrough Properties: A life science real estate development company fostering innovation through collaboration. Candid Therapeutics: Focused on developing drugs for autoimmune diseases and immunological conditions. Cell Design Labs: Developing cell-based therapies for cancer using the body's immune system. Kite Pharma: Leader in autologous CAR T therapies, known for FDA-approved Yescarta™. Kronos Bio: Developing first-in-class therapies for challenging cancer targets. Neogene Therapeutics: Specializes in next-generation T-cell receptor therapies for solid tumors, now part of AstraZeneca. Symbiotic Capital: Provides credit solutions to support scientific innovation in healthcare. Vida Ventures: Dedicated to funding breakthroughs in biomedicine.
Common questions
What to know about Two River
Upseed classifies Two River under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
May 6, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.