Organization · Venture Capital
SeedFolio
SeedFolio is a seed-stage venture capital firm based in San Diego, focusing on early investments in innovative technologies that address health and environmental challenges.
Overview
What SeedFolio does
What SeedFolio is
SeedFolio is a seed-stage venture capital firm based in San Diego, focusing on early investments in innovative technologies that address health and environmental challenges.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2020
- Approximate age
- About 6 years
- Structured capabilities
- Funder
- Last reviewed
- April 26, 2026
Official channels
Find SeedFolio elsewhere
Open the official website or a supported primary organization account.
Capability profile
SeedFolio as a funder
Investment thesis
SeedFolio invests in early-stage companies developing innovative technologies that address health and environmental challenges, aiming for high reward/risk ratios.
Focus narrative
SeedFolio targets investments in companies creating novel technologies aimed at conquering diseases and promoting environmental sustainability. Their strategy prioritizes sectors related to healthcare and clean technologies, with a keen interest in startups that demonstrate a credible path to large returns.
Value beyond capital
SeedFolio adds value to its portfolio companies through strategic guidance, leveraging the expertise of its team in healthcare, biotechnology, and technology development. The firm focuses on helping startups refine their business models, navigate regulatory landscapes, and connect with potential customers and partners.
Terms and economics
- Typical check
- $300,000–$2,000,000
- Sweet spot
- $300,000
Focus and fit
- Stages
- Seed · Pre-seed · Series A
- Sectors
- Healthcare · Biotech · Digital Health · Diagnostics · Medical Devices · AI · IoT
- Regions
- North AmericaUnited States
Availability
- Currently deploying
- No
Portfolio and track record
- Recorded notable exits
- DTX Pharma
Portfolio context
Notable portfolio companies include: Allotrope Medical: Acquired company improving lower pelvic surgeries with faster ureter identification. AmplifiDx: A point-of-care molecular diagnostics platform that is faster and cheaper than traditional PCR. Amplo Biotechnology: Focused on treating neuro-muscular junction diseases through gene therapy. Anvil Diagnostics: Develops a rapid pathogen identification system for sepsis. Earthgrid: Develops tunnel-boring technology for renewable energy projects.
Common questions
What to know about SeedFolio
Upseed classifies SeedFolio under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
April 26, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.