Organization · Venture Capital

PFM Health Sciences

PFM Health Sciences is a healthcare investment advisor based in San Francisco, specializing in managing public and private investments in biopharma, medical technology, life sciences, and healthcare services.

Venture CapitalFunder

Overview

What PFM Health Sciences does

What PFM Health Sciences is

PFM Health Sciences is a healthcare investment advisor based in San Francisco, specializing in managing public and private investments in biopharma, medical technology, life sciences, and healthcare services.

How it participates in the startup ecosystem

The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.

Operational profile

Organization status and context

Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.

Operational status
Active
Organization type
Venture Capital
Founded
Founded in 2004
Approximate age
About 22 years
Structured capabilities
Funder
Last reviewed
April 24, 2026

Official channels

Find PFM Health Sciences elsewhere

Open the official website or a supported primary organization account.

Capability profile

PFM Health Sciences as a funder

Investment thesis

PFM Health Sciences focuses on biopharma, medical technology, life sciences, and healthcare services, providing growth and mezzanine capital for private companies. Their investment strategy combines bottom-up fundamental research with macro-level analysis, emphasizing disruptive innovation.

Focus narrative

PFM Health Sciences invests in various subsectors within the healthcare industry, including biopharma, medical technology, life sciences, and healthcare services. The firm utilizes a subsector specialist approach to identify and capitalize on long-term growth opportunities, allowing for flexibility across the capital structure by investing in both public and private companies.

Value beyond capital

PFM Health Sciences adds value to its portfolio companies through a combination of deep industry expertise, strategic guidance, and access to a broad network of resources. Their approach includes bottom-up research and a focus on disruptive innovation, enabling them to support companies in achieving their growth objectives.

Terms and economics

Typical check
$1,000,000–$50,000,000
Sweet spot
$10,000,000

Focus and fit

Stages
Growth Equity · Series A · Series B

Availability

Currently deploying
Yes

Portfolio and track record

Recorded portfolio count
62
Recorded notable exits
Juno Therapeutics and Blueprint Medicines

Portfolio context

Notable investments include Outset Medical, Mendaera, and Apella, among others. The firm has a history of investing in significant healthcare companies such as Juno Therapeutics and Blueprint Medicines.

Common questions

What to know about PFM Health Sciences

Upseed classifies PFM Health Sciences under the Venture Capital organization type. Its current public profile includes funder capabilities.

Next step

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Source and update disclosure

Know what this page is based on

Source basis

Public organization and program material, official websites, and structured Upseed records.

Last reviewed

April 24, 2026

Known limits

Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.

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