Organization · Venture Capital
LongGame
LongGame is a venture capital firm based in the United States that invests in longevity biotech companies focused on extending healthy human lifespan. The firm emphasizes scalable solutions that benefit society as a whole.
Overview
What LongGame does
What LongGame is
LongGame is a venture capital firm based in the United States that invests in longevity biotech companies focused on extending healthy human lifespan. The firm emphasizes scalable solutions that benefit society as a whole.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Structured capabilities
- Funder
- Last reviewed
- May 2, 2026
Official channels
Find LongGame elsewhere
Open the official website or a supported primary organization account.
Capability profile
LongGame as a funder
Investment thesis
LongGame invests in technologies designed to extend human life beyond current limits, targeting a minimum increase of 10 years in healthy lifespan through radical lifespan extension.
Focus narrative
LongGame exclusively invests in technologies aimed at extending human life, specifically targeting a minimum increase of 10 years in healthy lifespan. The firm emphasizes scalable solutions in various biotech fields, including AI, synthetic biology, stem cell therapies, gene sequencing and editing, protein engineering, and tissue engineering.
Value beyond capital
LongGame adds value to its portfolio companies by providing strategic guidance, access to a network of industry experts, and support in navigating the complexities of the longevity biotech landscape. The firm is committed to fostering innovation that addresses the root causes of aging and promotes scalable solutions for healthy lifespan extension.
Focus and fit
- Stages
- Pre-seed · Seed
- Regions
- United States
Availability
- Currently deploying
- Not published
Portfolio and track record
Portfolio context
LongGame's portfolio includes companies such as Cirrus Therapeutics, which develops gene therapies for age-related vision loss; Repair Biotechnologies, focusing on cholesterol-degrading therapies for cardiovascular disease; and Totality Biosciences, working on plant synthetic biology for chronic diseases. Other notable companies include Revel Pharma, Syntax Bio, and Aperture Therapeutics, all targeting various aspects of aging and age-related diseases.
Common questions
What to know about LongGame
Upseed classifies LongGame under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
May 2, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.