Organization · Accelerator

IndieBio

IndieBio is a leading biotech accelerator under SOSV, focusing on early-stage startups in biotechnology and deep tech. It provides unique access to wet lab infrastructure and significant funding to support innovative solutions for human and planetary health.

AcceleratorFunderProgram host

Overview

What IndieBio does

What IndieBio is

IndieBio is a leading biotech accelerator under SOSV, focusing on early-stage startups in biotechnology and deep tech. It provides unique access to wet lab infrastructure and significant funding to support innovative solutions for human and planetary health.

How it participates in the startup ecosystem

The current public profile supports funder and program host capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.

Operational profile

Organization status and context

Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.

Operational status
Active
Organization type
Accelerator
Founded
Founded in 2014
Approximate age
About 12 years
Structured capabilities
Funder · Program host
Last reviewed
March 27, 2026
What Accelerator means

An accelerator is a structured, short-term program designed to speed up a startup's progress toward product-market fit, traction, fundraising, or scale.

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Official channels

Find IndieBio elsewhere

Open the official website or a supported primary organization account.

Capability profile

IndieBio as a funder

Investment thesis

IndieBio invests in early-stage biotech startups that address human and planetary health challenges, leveraging biology to create innovative solutions across various sectors.

Focus narrative

IndieBio invests in a diverse range of sectors where biology can drive innovation, including climate tech, food, therapeutics, and materials. The accelerator supports startups primarily at the pre-seed stage and continues to provide follow-on investments, fostering a robust ecosystem for biotech entrepreneurs.

Value beyond capital

IndieBio provides significant value to its portfolio companies through access to BSL-2 wet lab facilities, scientific mentorship, business development support, and a global network of over 1,000 portfolio companies. This infrastructure and support system is designed to accelerate the growth and success of biotech startups.

Terms and economics

Typical check
$250,000–$525,000
Sweet spot
$250,000

Focus and fit

Stages
Pre-seed · Seed · Seed+ · Series A
Sectors
Biotech · Climate · Food and AgTech · Healthcare · Energy · Materials Science
Regions
Global · North America

Availability

Currently deploying
Yes

Portfolio and track record

Recorded portfolio count
270
Recorded notable exits
NotCo, UPSIDE Foods, and MycoWorks

Portfolio context

IndieBio has funded over 270 companies globally, with notable portfolio companies such as: Zymochem: Develops sustainable materials using patented Carbon-Conserving (C2) microbes. Avalo.ai: A gene discovery platform for breeding climate-resilient crops. Ten63 Therapeutics: Focuses on in silico drug design. Hoofprint Biome: Works on solutions to reduce methane emissions from cattle. Calder Biosciences: Develops next-generation vaccines.

Capability profile

IndieBio as a program host

Program thesis

IndieBio is a program of SOSV that supports innovative ideas in biotechnology, focusing on early-stage biotech startups addressing human and planetary health challenges.

Focus narrative

IndieBio invests in a diverse range of sectors where biology can create innovative solutions, including climate tech, food, therapeutics, and materials. The organization emphasizes diversity within its portfolio, particularly supporting female founders and companies that address pressing global issues.

Value and support

IndieBio offers hands-on lab access, scientific mentorship, business development support, and access to a global network of over 1,000 portfolio companies. The program is designed to provide both capital and critical infrastructure for biotech founders.

Additional public guidance

Q: What is the duration of the program? A: The program lasts approximately 4 months. Q: How many cohorts are there each year? A: IndieBio runs 2 cohorts per year. Q: What is the initial investment amount? A: The initial investment is $250K for 6-8% equity.

Terms and economics

Indicative investment
$250,000
Indicative equity
6%

Format and cadence

Typical duration
16 weeks
Typical cohort
15 companies
Cohorts per year
2
Format
In Person

Availability

Application state
Accepting

Focus and fit

Stages
Accelerator · Pre-seed · Seed
Regions
Global · North America

Alumni and track record

Alumni context

Notable alumni companies include Zymochem, which develops sustainable materials; Avalo.ai, a gene discovery platform for climate-resilient crops; Ten63 Therapeutics, focusing on in silico drug design; Hoofprint Biome, which mitigates methane emissions from cattle; and Calder Biosciences, developing next-generation vaccines.

Common questions

What to know about IndieBio

Upseed classifies IndieBio under the Accelerator organization type. Its current public profile includes funder and program host capabilities.

Next step

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Source and update disclosure

Know what this page is based on

Source basis

Public organization and program material, official websites, and structured Upseed records.

Last reviewed

March 27, 2026

Known limits

Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.

Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.