Organization · Venture Capital
Impact Science Ventures
Impact Science Ventures is a venture capital firm based in the United States that focuses on impact investing in early-stage companies commercializing scientific innovations across critical sectors such as energy, materials, and agriculture.
Overview
What Impact Science Ventures does
What Impact Science Ventures is
Impact Science Ventures is a venture capital firm based in the United States that focuses on impact investing in early-stage companies commercializing scientific innovations across critical sectors such as energy, materials, and agriculture.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2021
- Approximate age
- About 5 years
- Structured capabilities
- Funder
- Last reviewed
- March 27, 2026
Official channels
Find Impact Science Ventures elsewhere
Open the official website or a supported primary organization account.
Capability profile
Impact Science Ventures as a funder
Investment thesis
Impact Science Ventures focuses on deep tech and hard science investing, leveraging scientific breakthroughs to address significant industry challenges, particularly in climate change and industrial decarbonization.
Focus narrative
ISV invests in early-stage companies that are focused on disrupting large markets through scientific innovations. The organization emphasizes sectors such as energy, materials, manufacturing, and agriculture, seeking multi-disciplinary teams that enhance supply chain resilience and facilitate the transition to cleaner energy and materials.
Value beyond capital
ISV adds value to its portfolio companies by leveraging partnerships with universities and government funding sources to de-risk technology before scaling. The organization also provides milestone-based pre-seed investments through its Activate investor partnership program, ensuring that portfolio companies have the necessary support to succeed.
Focus and fit
- Stages
- Pre-seed · Seed · Seed+ · Series A · Series B
- Regions
- United States
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 9
Portfolio context
Notable portfolio companies include: Twelve: Transforms CO2 into jet fuel and electrochemicals at scale. Brimstone: Produces alumina to bolster the U.S. aluminum supply chain. Fervo Energy: Engaged in next-generation geothermal energy solutions. Umaro: Develops sustainable bioplastics from seaweed waste. Concerto Biosciences: Innovates in microbiome-based therapies. Gradient: Focuses on heat pump technology for energy efficiency. Antora Energy: Specializes in thermal energy storage for industrial decarbonization. Sepion Technologies: Works on advanced battery membranes. Liminal: Provides battery health diagnostics.
Common questions
What to know about Impact Science Ventures
Upseed classifies Impact Science Ventures under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
March 27, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.