Organization · Venture Capital
i2E, Inc.
i2E, Inc. is a non-profit organization based in Oklahoma that supports local entrepreneurs by providing resources, infrastructure, and investment through its venture arm, Plains Ventures. It focuses on early-stage companies across various sectors.
Overview
What i2E, Inc. does
What i2E, Inc. is
i2E, Inc. is a non-profit organization based in Oklahoma that supports local entrepreneurs by providing resources, infrastructure, and investment through its venture arm, Plains Ventures. It focuses on early-stage companies across various sectors.
How it participates in the startup ecosystem
The current public profile supports funder and community capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 1998
- Approximate age
- About 28 years
- Structured capabilities
- Funder · Community
- Last reviewed
- April 22, 2026
Official channels
Find i2E, Inc. elsewhere
Open the official website or a supported primary organization account.
Capability profile
i2E, Inc. as a funder
Investment thesis
i2E, Inc. supports local entrepreneurs and innovators in Oklahoma by providing resources, infrastructure, and guidance to help them build, launch, and grow their ideas.
Focus narrative
i2E invests in a variety of sectors including healthcare, software/IT, biotech/pharma, energy and environment, and manufacturing. The organization provides services such as venture advisory, access to funding, and support for startups at various stages of development, primarily within Oklahoma.
Value beyond capital
i2E provides comprehensive support to its portfolio companies through venture advisory services, access to funding, and a robust network of resources aimed at fostering innovation and growth in Oklahoma's entrepreneurial ecosystem.
Focus and fit
- Stages
- Friends and Family · Angel · Accelerator · Pre-seed · Seed · Seed+ · Series A · Series B · Growth Equity
- Regions
- United StatesNorth America
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 250
- Recorded notable exits
- Selexys Pharmaceuticals, Crescendo Bioscience, and Alkami
Portfolio context
Notable portfolio companies include: 10-9 Technologies (energy and environment, founded in 2015), Aevus Precision Diagnostics (healthcare, founded in 2019), BioLytx Pharmaceuticals Corp (biotech/pharma, founded in 2005), Moleculera Biosciences (biotech/pharma, founded in 2011), and Wheeler Bio (biotech/pharma, founded in 2020).
Capability profile
i2E, Inc. as a community
Community overview
i2E, Inc. is a 501(c)(3) non-profit organization founded in 1998 and based in Oklahoma. It focuses on supporting local entrepreneurs and innovators by providing resources, infrastructure, and guidance to help them build, launch, and grow their ideas. i2E is recognized as a key partner in Oklahoma's economic development and innovation ecosystem.
Community focus
i2E invests in a variety of sectors including healthcare, software/IT, biotech/pharma, energy and environment, and manufacturing. The organization provides services such as venture advisory, access to funding, and support for startups at various stages of development. It operates primarily within Oklahoma.
Member value
Members benefit from access to venture advisory services, funding opportunities, and a supportive network aimed at fostering innovation and entrepreneurship in Oklahoma.
Membership
- Pricing models
- free
Format and cadence
- Modality
- in-person
- Schedule
- rolling-admissions
- Commitment
- light
Availability
- Membership state
- Accepting
Audience and fit
- Audience
- Founders · Investors · Operators
- Benefits
- network-access and mentorship
- Program types
- community
- Selection criteria
- open
- Stages
- Pre-seed · Seed · Seed+
- Regions
- United States
Common questions
What to know about i2E, Inc.
Upseed classifies i2E, Inc. under the Venture Capital organization type. Its current public profile includes funder and community capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
April 22, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.