Organization · Venture Capital
Fifty Years
Fifty Years is a pre-seed and seed-focused venture capital firm based in the United States, dedicated to supporting entrepreneurs who leverage technology to tackle significant global challenges. The firm emphasizes impact investing and aids scientists and engineers in their transition to entrepreneurship.
Overview
What Fifty Years does
What Fifty Years is
Fifty Years is a pre-seed and seed-focused venture capital firm based in the United States, dedicated to supporting entrepreneurs who leverage technology to tackle significant global challenges. The firm emphasizes impact investing and aids scientists and engineers in their transition to entrepreneurship.
How it participates in the startup ecosystem
The current public profile supports funder and program host capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2016
- Approximate age
- About 10 years
- Structured capabilities
- Funder · Program host
- Last reviewed
- March 27, 2026
Official channels
Find Fifty Years elsewhere
Open the official website or a supported primary organization account.
Capability profile
Fifty Years as a funder
Investment thesis
Fifty Years supports founders leveraging technology to tackle significant global challenges, with a focus on transitioning scientists and engineers into entrepreneurship.
Focus narrative
Fifty Years invests in early-stage companies across various sectors, particularly in deep tech. While sector agnostic, the firm shows enthusiasm for climate tech, synthetic biology, health and mental health, space tech, connectivity, and food tech. They prefer companies with initial go-to-market strategies in North America or Europe, prioritizing those that aim for positive societal impact.
Value beyond capital
Fifty Years provides significant value to its portfolio companies by leveraging its extensive network of founders and industry experts. The firm focuses on mentorship and guidance, particularly for scientists and engineers transitioning into entrepreneurship, ensuring that they have the resources and support needed to succeed in their ventures.
Focus and fit
- Stages
- Pre-seed · Seed
- Sectors
- Climate & SustainabilityBiotech & Life SciencesHealthcareSpace TechConnectivityFood & Agriculture
- Regions
- EuropeNorth America
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 100
Portfolio context
Fifty Years has supported numerous innovative companies, including: Plasmidsaurus: Ultra-fast DNA sequencing as a service. Digital Biology: Revolutionizing functional sequencing. Clippership: Autonomous sailboats aimed at decarbonizing maritime shipping. Medra: Automating repetitive wetlab tasks using robotics and computer vision. Type III: Focused on rebuilding the American tech tree. Enoda: Transforming cells into cures for various diseases. Huminly: Utilizing enzymes to create infinitely recyclable clothing. The firm has helped launch over 100 companies through initiatives like the 5050 program, which assists scientists and engineers in starting deep tech startups.
Capability profile
Fifty Years as a program host
Program thesis
Fifty Years aims to support founders who utilize technology to address significant global challenges, particularly in deep tech.
Focus narrative
The firm invests in early-stage companies across various sectors, with a strong interest in deep tech. While sector agnostic, Fifty Years is particularly enthusiastic about climate tech, synthetic biology, health and mental health, space tech, connectivity, and food tech. They prioritize companies with initial go-to-market strategies in North America or Europe and those that aim for positive societal impact.
Value and support
Founders participating in Fifty Years' initiatives gain access to funding, mentorship from experienced entrepreneurs, and a network of industry experts. The firm also provides resources to help launch and scale deep tech startups, particularly through its 5050 program designed for scientists and engineers.
Availability
- Application state
- Not published
Focus and fit
- Stages
- Pre-seed · Seed
- Regions
- EuropeNorth America
Alumni and track record
Alumni context
Fifty Years has supported over 100 companies, including notable alumni such as Plasmidsaurus, which offers ultra-fast DNA sequencing; Digital Biology, revolutionizing functional sequencing; and Clippership, which focuses on decarbonizing maritime shipping with autonomous sailboats.
Programs hosted by Fifty Years
These Programs have a direct canonical host relationship to this Organization.
Common questions
What to know about Fifty Years
Upseed classifies Fifty Years under the Venture Capital organization type. Its current public profile includes funder and program host capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
March 27, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.