Organization · Venture Capital

EcoR1 Capital, LLC

EcoR1 Capital, LLC is a San Francisco-based investment firm specializing in the biotechnology sector, focusing on innovative therapeutics. It operates as a crossover fund, investing in both late-stage private rounds and public equity.

Venture CapitalFunder

Overview

What EcoR1 Capital, LLC does

What EcoR1 Capital, LLC is

EcoR1 Capital, LLC is a San Francisco-based investment firm specializing in the biotechnology sector, focusing on innovative therapeutics. It operates as a crossover fund, investing in both late-stage private rounds and public equity.

How it participates in the startup ecosystem

The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.

Operational profile

Organization status and context

Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.

Operational status
Active
Organization type
Venture Capital
Founded
Founded in 2012
Approximate age
About 14 years
Structured capabilities
Funder
Last reviewed
April 10, 2026

Official channels

Find EcoR1 Capital, LLC elsewhere

Open the official website or a supported primary organization account.

Capability profile

EcoR1 Capital, LLC as a funder

Investment thesis

EcoR1 Capital focuses on investing in biotechnology companies developing innovative therapeutics aimed at improving patient outcomes. The firm emphasizes long-term partnerships with entrepreneurs committed to advancing therapeutic innovation.

Focus narrative

EcoR1 Capital invests primarily in the biotechnology sector, targeting companies engaged in the development of therapeutics for various diseases. The firm seeks to identify and support innovative solutions that can significantly improve patient outcomes.

Value beyond capital

EcoR1 Capital adds value to its portfolio companies through strategic financing, scientific rigor, and a commitment to long-term partnerships. The firm leverages its expertise in the biotechnology sector to support entrepreneurs in navigating the complexities of drug development and commercialization.

Terms and economics

Typical check
$1,000,000–$50,000,000
Sweet spot
$10,000,000

Focus and fit

Stages
Seed · Series A · Series B · Series C · Growth Equity · Pre-IPO
Regions
Global · North America

Availability

Currently deploying
Yes

Portfolio and track record

Recorded portfolio count
30

Portfolio context

Notable portfolio companies include Accent Therapeutics, which focuses on RNA-targeted therapies; Actio BioSciences, developing novel therapeutics; and Affinia Therapeutics, working on gene therapies. Other significant investments include AlloVir, Akouos, and Arcus Biosciences, among many others, showcasing a diverse range of therapeutic innovations.

Common questions

What to know about EcoR1 Capital, LLC

Upseed classifies EcoR1 Capital, LLC under the Venture Capital organization type. Its current public profile includes funder capabilities.

Next step

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Source and update disclosure

Know what this page is based on

Source basis

Public organization and program material, official websites, and structured Upseed records.

Last reviewed

April 10, 2026

Known limits

Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.

Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.