Organization · Venture Capital
Define Ventures
Define Ventures is a venture capital firm based in Silicon Valley that focuses on early-stage digital health companies. With approximately $800 million in assets under management, it invests in companies at the incubation, seed, Series A, and Series B stages.
Overview
What Define Ventures does
What Define Ventures is
Define Ventures is a venture capital firm based in Silicon Valley that focuses on early-stage digital health companies. With approximately $800 million in assets under management, it invests in companies at the incubation, seed, Series A, and Series B stages.
How it participates in the startup ecosystem
The current public profile supports funder and event host and publisher capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Structured capabilities
- Funder · Event host · Publisher
- Last reviewed
- March 27, 2026
Official channels
Find Define Ventures elsewhere
Open the official website or a supported primary organization account.
Capability profile
Define Ventures as a funder
Investment thesis
Define Ventures focuses on the convergence of healthcare and technology, investing in early-stage digital health companies that are redefining healthcare delivery and access.
Focus narrative
Define Ventures invests exclusively in early-stage health tech companies, targeting the incubation, seed, Series A, and Series B stages. The firm seeks to partner with entrepreneurs who are leveraging technology to transform healthcare delivery and improve patient outcomes.
Value beyond capital
Define Ventures adds value to its portfolio companies through strategic guidance, leveraging its deep understanding of the healthcare ecosystem and technology trends. The firm actively supports entrepreneurs in navigating the complexities of healthcare, facilitating connections within the industry, and providing insights that drive growth and innovation.
Focus and fit
- Stages
- Seed · Series A · Series B
- Sectors
- HealthcareDigital Health
- Regions
- North America
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 21
- Recorded notable exits
- Hims & Hers, Livongo, and Evolent Health
Portfolio context
Notable portfolio companies include: Hims & Hers: A health and wellness platform focused on improving access to healthcare. Unite Us: A technology platform that connects community services to improve whole-person health. Cohere Health: A company leveraging AI and machine learning to enhance clinical care experiences. FOLX Health: A digital healthcare platform tailored for the LGBTQIA+ community. 9am: A personalized care delivery platform for patients with cardiometabolic conditions. Dexcare: A patient access optimization platform that manages digital demand across various lines of care.
Capability profile
Define Ventures as an event host
Event focus
Define Ventures focuses on early-stage health tech companies, emphasizing partnerships with entrepreneurs who are redefining healthcare through innovative solutions and technology. The firm targets incubation, seed, Series A, and Series B stages, aiming to shape the future of healthcare with a technology-driven mindset.
Participant value
Define Ventures provides significant value to its portfolio companies by leveraging deep insights into the healthcare ecosystem and a technology-driven approach. The firm has a strong track record of driving shareholder value and supporting companies at various stages of growth.
Format and cadence
- Event types
- summit
- Modality
- in-person
- Startups can present
- No
Availability
- Registration state
- Not currently accepting
- Next recorded event
- January 8, 2024
Audience and fit
- Stages
- Pre-seed · Seed · Series A · Series B
- Audience
- Founders · Investors
- Sectors
- Healthcare
- Regions
- North America
Capability profile
Define Ventures as a publisher
Editorial focus
Define Ventures is dedicated to investing in early-stage health tech companies, emphasizing partnerships with entrepreneurs who are redefining healthcare through innovative solutions and technology. The firm manages six funds with approximately $800 million in assets under management, targeting incubation, seed, Series A, and Series B stages.
Audience value
Define Ventures provides value by leveraging deep industry knowledge and a technology-driven approach to support innovative health tech companies, ultimately aiming to reshape the future of healthcare.
Format and cadence
- Content formats
- research-report and blog
- Primary platform
- definevc.com
Availability
- Guest pitch state
- Not currently accepting
Audience and focus
- Audience
- Investors · Founders
- Sectors
- Healthcare
- Regions
- North America
Flagship work and coverage
Flagship properties
Define Ventures publishes insights and reports on healthcare and technology trends, including the 'Health Tech's Defining Decade' report. The firm also hosts events such as the Define Ventures AI + Healthcare Summit and Founders Summit 2025.
Notable coverage
Define Ventures has been featured in prominent publications such as MobiHealthNews, Fierce Healthcare, and STAT News, highlighting its focus on digital health and its significant portfolio exits.
Common questions
What to know about Define Ventures
Upseed classifies Define Ventures under the Venture Capital organization type. Its current public profile includes funder, event host, and publisher capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
March 27, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.