Organization · Venture Capital
Cold Harbor Venture Capital
Cold Harbor Venture Capital is a venture capital firm based in Charleston, South Carolina, focused on investing in pre-seed to Series A healthcare AI startups. They support founders advancing healthcare through innovative software solutions.
Overview
What Cold Harbor Venture Capital does
What Cold Harbor Venture Capital is
Cold Harbor Venture Capital is a venture capital firm based in Charleston, South Carolina, focused on investing in pre-seed to Series A healthcare AI startups. They support founders advancing healthcare through innovative software solutions.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Structured capabilities
- Funder
- Last reviewed
- April 28, 2026
Official channels
Find Cold Harbor Venture Capital elsewhere
Open the official website or a supported primary organization account.
Capability profile
Cold Harbor Venture Capital as a funder
Investment thesis
Cold Harbor Venture Capital backs founders advancing healthcare through artificial intelligence and software that enhances care delivery and clinical decision-making.
Focus narrative
Cold Harbor Venture Capital invests in pre-seed through Series A B2B healthcare AI startups. Their focus includes technologies that enhance clinical decision support, workflow automation, healthcare infrastructure software, and AI-enabled medical devices. The firm is particularly interested in applied machine learning for diagnostics and platforms that accelerate biomedical and life sciences discovery.
Value beyond capital
Cold Harbor Venture Capital implements a structured 100-day sprint for each company post-funding, where founders select three scaling avenues for support, ensuring tailored guidance and resources to accelerate growth.
Focus and fit
- Stages
- Pre-seed · Seed · Series A
- Regions
- North America
Availability
- Currently deploying
- Not published
Portfolio and track record
Portfolio context
Cold Harbor Venture Capital has launched three funds: The Mayflower ($75 million, 2026), The Arbella ($150 million, 2029), and The Constitution ($250 million, 2032), aimed at supporting innovative healthcare technologies and sustainable healthcare institutions.
Common questions
What to know about Cold Harbor Venture Capital
Upseed classifies Cold Harbor Venture Capital under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
April 28, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.