Organization · Venture Capital

CLI Ventures

CLI Ventures is an investment organization based in Palo Alto, California, focusing on early to late-stage startups in sectors like technology and biopharmaceuticals.

Venture CapitalFunder

Overview

What CLI Ventures does

What CLI Ventures is

CLI Ventures is an investment organization based in Palo Alto, California, focusing on early to late-stage startups in sectors like technology and biopharmaceuticals.

How it participates in the startup ecosystem

The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.

Operational profile

Organization status and context

Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.

Operational status
Active
Organization type
Venture Capital
Structured capabilities
Funder
Last reviewed
March 27, 2026

Official channels

Find CLI Ventures elsewhere

Open the official website or a supported primary organization account.

Capability profile

CLI Ventures as a funder

Investment thesis

CLI Ventures focuses on the next generation of healthcare and data analytics companies, investing in biotechnology, diagnostics, therapeutics, and software.

Focus narrative

CLI Ventures invests in a diverse range of sectors, particularly technology and biopharmaceuticals. The organization is committed to supporting companies at various stages of development, ensuring they have the resources and guidance needed to succeed.

Value beyond capital

CLI Ventures adds value to its portfolio companies by leveraging its extensive network and expertise in healthcare and technology sectors. The firm operates as a follow-on investor, providing additional funding and support to help companies scale and succeed in competitive markets.

Terms and economics

Typical check
$5,000,000–$10,000,000

Focus and fit

Stages
Friends and Family · Angel · Accelerator · Pre-seed · Seed · Seed+ · Series A · Series A+ · Series B · Series B+ · Series C · Series C+ · Series D · Series E · Series F · Growth Equity · Pre-IPO · Ipo · Secondary · Bridge · Recap
Sectors
Healthcare · Biotech · Diagnostics · Robotics
Regions
Asia · Global · North America

Availability

Currently deploying
Yes

Portfolio and track record

Recorded portfolio count
200

Portfolio context

Notable portfolio companies include: Compass: A technology-driven real estate platform that facilitates the buying, selling, and renting of homes. CRISPR Therapeutics: A biopharmaceutical company utilizing CRISPR/Cas9 gene-editing technology to develop medicines for serious diseases. Guardant Health: A company providing genomic cancer testing through a blood draw, helping oncologists match patients with targeted therapies.

Common questions

What to know about CLI Ventures

Upseed classifies CLI Ventures under the Venture Capital organization type. Its current public profile includes funder capabilities.

Next step

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Source and update disclosure

Know what this page is based on

Source basis

Public organization and program material, official websites, and structured Upseed records.

Last reviewed

March 27, 2026

Known limits

Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.

Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.