Organization · Venture Capital
Black Opal Ventures
Black Opal Ventures is a venture capital firm based in New York City and San Francisco, focusing on early-phase investments in frontier technologies at the intersection of healthcare and security.
Overview
What Black Opal Ventures does
What Black Opal Ventures is
Black Opal Ventures is a venture capital firm based in New York City and San Francisco, focusing on early-phase investments in frontier technologies at the intersection of healthcare and security.
How it participates in the startup ecosystem
The current public profile supports funder and publisher capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2021
- Approximate age
- About 5 years
- Structured capabilities
- Funder · Publisher
- Last reviewed
- April 9, 2026
Official channels
Find Black Opal Ventures elsewhere
Open the official website or a supported primary organization account.
Capability profile
Black Opal Ventures as a funder
Investment thesis
Black Opal Ventures invests at the intersection of healthcare and technology, focusing on innovative solutions to address significant global challenges in these sectors.
Focus narrative
Black Opal Ventures emphasizes collaboration across industries to create transformational solutions. Their investment strategy targets unsolved problems in U.S. healthcare and security, with a focus on companies that can deliver impactful solutions in these areas. The firm recognizes the substantial market potential, with healthcare spending projected to exceed $6 trillion by 2028 and security spending forecasted at $2.7 trillion.
Value beyond capital
Black Opal Ventures adds value to its portfolio companies through strategic guidance, access to a network of industry experts, and support in navigating the complexities of the healthcare and security sectors. The firm also runs the Black Opal Venture Fellows Program, aimed at developing talent and fostering innovation.
Terms and economics
- Typical check
- $250,000–$2,000,000
Focus and fit
- Stages
- Seed · Series A · Series B
- Regions
- United States
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 15
Portfolio context
Notable portfolio companies include Intellihealth, focusing on obesity and metabolic health; Conceivable Life Sciences, specializing in infertility and reproductive health; Optellum, which uses AI for lung cancer diagnostics; Hyro, providing conversational AI for healthcare; Empatica, known for wearables in neurology; and TigerGraph, which offers graph analytics for healthcare data.
Capability profile
Black Opal Ventures as a publisher
Editorial focus
Black Opal Ventures is a venture capital firm that focuses on investing in early-phase companies leveraging technology to address significant challenges in healthcare, security, and infrastructure. The firm emphasizes diverse perspectives in driving innovation and creating impactful solutions, targeting sectors such as healthcare, security, infrastructure, hardware, and technology.
Audience value
Black Opal Ventures aims to create a positive impact through its portfolio companies, which address pressing problems in healthcare and technology. The firm is committed to measuring both financial performance and social impact.
Format and cadence
- Content formats
- blog and newsletter
Availability
- Guest pitch state
- Not currently accepting
Audience and focus
- Audience
- Investors · Founders
- Sectors
- Healthcare
- Regions
- North America
Flagship work and coverage
Flagship properties
Black Opal Ventures publishes insights and news through their blog, which includes articles on various topics related to their investment focus. They also maintain a newsletter for updates.
Notable coverage
Black Opal Ventures has been featured in various media outlets including BusinessWire, VCJ, VatorNews, and Femtech Insider, highlighting their commitment to impact investing and their diverse leadership.
Common questions
What to know about Black Opal Ventures
Upseed classifies Black Opal Ventures under the Venture Capital organization type. Its current public profile includes funder and publisher capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
April 9, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.