Organization · Venture Capital
Ascension Ventures
Ascension Ventures is a healthcare venture fund based in St. Louis, Missouri, focusing on strategic investments in early to late-stage companies across healthcare sectors. They manage over $1 billion in capital and connect healthcare systems with innovators.
Overview
What Ascension Ventures does
What Ascension Ventures is
Ascension Ventures is a healthcare venture fund based in St. Louis, Missouri, focusing on strategic investments in early to late-stage companies across healthcare sectors. They manage over $1 billion in capital and connect healthcare systems with innovators.
How it participates in the startup ecosystem
The current public profile supports funder capabilities. Each capability below is shown separately so organization identity and role-specific information do not get conflated.
Operational profile
Organization status and context
Organization status describes the entity itself. Funding and program availability appear within the relevant capability profile.
- Operational status
- Active
- Organization type
- Venture Capital
- Founded
- Founded in 2001
- Approximate age
- About 25 years
- Structured capabilities
- Funder
- Last reviewed
- March 17, 2026
Official channels
Find Ascension Ventures elsewhere
Open the official website or a supported primary organization account.
Capability profile
Ascension Ventures as a funder
Investment thesis
Ascension Ventures focuses on transforming healthcare by connecting healthcare systems with emerging innovators to develop scalable solutions for complex challenges.
Focus narrative
Ascension Ventures invests in healthcare information technology, services, and medical devices and diagnostics. The organization typically invests between $10 million and $20 million per company, targeting early- to late-stage companies within three to five years of a potential liquidating event. Their investment strategy emphasizes sustainable competitive advantages and compelling benefits that influence market adoption.
Value beyond capital
Ascension Ventures provides portfolio companies with unmatched market insight, validation, and pilot opportunities through its strategic access to a large network of healthcare facilities and professionals. This connection offers a unique advantage for startups seeking to validate their solutions in real-world healthcare settings.
Terms and economics
- Typical check
- $10,000,000–$20,000,000
Focus and fit
- Stages
- Friends and Family · Angel · Accelerator · Pre-seed · Seed · Seed+ · Series A · Series A+ · Series B · Series B+ · Series C · Series C+ · Series D · Series E · Series F · Growth Equity
- Sectors
- Healthcare · Health Data · Health Platforms · Medical Devices · Health Insurance Tech · Diagnostics · Telemedicine · Pharma Tech · Digital Health
- Regions
- United States
Availability
- Currently deploying
- Yes
Portfolio and track record
- Recorded portfolio count
- 104
- Recorded notable exits
- Phreesia, Syapse, and United Surgical Partners International
Portfolio context
Ascension Ventures has a diverse portfolio of 104 companies, including notable names such as Phreesia (IPO, healthcare payments), Syapse (precision medicine), and United Surgical Partners International. The fund has achieved a high exit rate with 1 unicorn, 8 IPOs, and 46 acquisitions.
Common questions
What to know about Ascension Ventures
Upseed classifies Ascension Ventures under the Venture Capital organization type. Its current public profile includes funder capabilities.
Source and update disclosure
Know what this page is based on
Source basis
Public organization and program material, official websites, and structured Upseed records.
Last reviewed
March 17, 2026
Known limits
Capability profiles appear only when a structured public profile also contains decision-useful role evidence. Terms and availability can change.
Upseed is an independent guide. It is not affiliated with or endorsed by the organization described on this page.